ORAL-GUT-BRAIN AXIS IN EXPERIMENTAL MODELS OF PERIODONTITIS: ASSOCIATING GUT DYSBIOSIS WITH NEURODEGENERATIVE DISEASES

Oral-Gut-Brain Axis in Experimental Models of Periodontitis: Associating Gut Dysbiosis With Neurodegenerative Diseases

Periodontitis is considered a non-communicable chronic disease caused by a dysbiotic microbiota, which generates a low-grade systemic inflammation that chronically damages the organism.Several studies have associated periodontitis with other chronic non-communicable diseases, such as cardiovascular or neurodegenerative diseases.Besides, the oral ba

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Adhesion molecules and differentiation syndrome: phenotypic and functional analysis of the effect of ATRA, As2O3, phenylbutyrate, and G-CSF in acute promyelocytic leukemia

Background and Objectives Differentiation Syndrome (DS) is a treatment complication which can occur in patients treated with acute promyelocytic leukemia (APL) with all transretinoic acid (ATRA) or As2O3, and is characterized by enhanced leukocyte transmigration.As2O3, Phenylbutyrate (PB) and G-CSF are known to potentiate ATRA effects.Our aim was t

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